Skip to main content
clickable transparency Dartmouth College Library
SearchMore Options
Home > New Acquisitions > July 2017 > Dana Biomedical Library

Dana Biomedical Library Acquisitions during July 2017

This news is available via an RSS feed RSS feed.

Big mechanisms in systems biology : big data mining, network modeling, and genome-wide data identification
Chen, Bor-Sen, author
London, United Kingdom ; Academic Press, an imprint of Elsevier, [2017]
Introduction to big mechanisms in systems biology -- System modeling and system identification methods for big mechanism in biological systems -- Procedure for exploring big mechanisms of systems biology through system identification and big database mining -- Big cellular mechanisms in the cell cycle by system identification and big data mining -- Big regulatory mechanisms in the transcriptional regulation control of gene expression using a stochastic system model and genome-wide experimental data -- Big mechanisms of information flow in cellular systems in response to environmental stress signals via system identification and data mining -- Big offensive and defensive mechanisms in systems immunity from system modeling and big data mining -- Big regeneration mechanisms via systems biology and big database mining methods -- Big tumorigenesis mechanisms in systems cancer biology via big data mining and network modeling -- Big evolutionary mechanisms of network robustness and signaling transductivity in aging and carcinogenic process by system modeling and database mining -- Big mechanisms of aging via system identification and big database mining -- Big drug design mechanisms via systems biology and big database mining.

"Big Mechanisms in Systems Biology: Big Data Mining, Network Modeling, and Genome-Wide Data Identification explains big mechanisms of systems biology by system identification and big data mining methods using models of biological systems. Systems biology is currently undergoing revolutionary changes in response to the integration of powerful technologies. Faced with a large volume of available literature, complicated mechanisms, small prior knowledge, few classes on the topics, and causal and mechanistic language, this is an ideal resource. This book addresses system immunity, regulation, infection, aging, evolution, and carcinogenesis, which are complicated biological systems with inconsistent findings in existing resources. These inconsistencies may reflect the underlying biology time-varying systems and signal transduction events that are often context-dependent, which raises a significant problem for mechanistic modeling since it is not clear which genes/proteins to include in models or experimental measurements. The book is a valuable resource for bioinformaticians and members of several areas of the biomedical field who are interested in an in-depth understanding on how to process and apply great amounts of biological data to improve research."--
On Display at Dana QH324.2 .C433 2017

Planktic foraminifers in the modern ocean
Schiebel, Ralf, author
Berlin : Springer-Verlag, [2017]
Species Classification, Test Architecture, Shell Ontogeny, Species Phylogeny -- Sampling Methods and Faunal Analysis -- Cultivation -- Biology, Cellular Ultrastructure, Host Symbiont Relationships, Trophic Activity and Nutrition, Reproduction -- Molecular Genetics in Modern Species -- Ecology -- Stable Isotopes -- Paleoceanography -- Element Ratios -- Sedimentation and Preservation of Tests -- Applications.

"This book provides a comprehensive overview of the taxonomy, biology, sedimentation, and carbonate geochemistry of modern species. Students, early career and advanced scientists alike will profit from a broad synthesis of the current understanding of planktic foraminifers as an ecological indicator, biogeochemical factories, and proxies in paleoceanography. The classification of modern species is amply illustrated with electron and light microscope images of morphotypes, addresses the state-of-the-art of molecular genetics of species, and provides a detailed guide for any laboratory analyses. The biology of planktic foraminifers is extensively discussed in chapters dedicated to the cellular ultrastructure, nutrition, symbionts, reproduction, ontogeny, and test architecture. Building on the biological prerequisites, the distribution of planktic foraminifers is discussed at regional to global scale. The geochemistry and sedimentation of tests are considered in relation to the ecology of the living animal. In the final chapter, which examines the most common methods in planktic foraminifer research, hands-on information is provided on sampling, processing and analyzing samples in the laboratory, as well as selected established methods for data interpretation. The various topics discussed in this book are aimed at the application of planktic foraminifers as sensitive indicators of the changing climate and marine environment."--Page 4 of cover.
On Display at Dana QL368.F6 S35 2017

Rooftops : islands in the sky
Jodidio, Philip, author
Cologne : Taschen, [2016]
As urban living intensifies in density and numbers, the city landscape expands both outwards and upwards. Architects and urban designers craft new and experimental structures while also investigating existing buildings for potential reinvention or expansion. In particular, the roof of a building, once a perfunctory structural element, is now a city space in and of itself, beloved for the capacity to eke out further room for living or to craft inspiring refuges away from the bustle of the metropolis.This international selection of urban rooftops catalogues a new urban dimension. Through over 50 bars, restaurants, temporary art installations, and gardens, it testifies to the variety of intelligent and exuberant designs that grace city summits from Sydney to Hong Kong, Oslo to Chicago.
On Display at Dana SB419.5 .J64 2016

Natural and constructed wetlands : nutrients, heavy metals and energy cycling, and flow
Jan Vymazal, editor
Switzerland : Springer, 2016
The book extends the knowledge on wetland ecosystem services based on the new research. The information combines the achievements gained in carbon sequestration, nutrient accumulation, macrophyte decomposition, wastewater treatment, global warming mitigation in constructed as well as natural wetlands across the globe. The book presents up-to-date results of ongoing research and the content of the book could be used by wetland scientists, researchers, engineers, designers, regulators, decision-makers, universities teachers, landscape engineers and landscape planners as well as by water authorities, water regulatory offices or wastewater treatment research institutions.
On Display at Dana QH541.5.M3 N38 2016

Force of nature : George Fell, founder of the natural areas movement
Pearson, Arthur Melville, author
Madison, Wisconsin : The University of Wisconsin Press, [2017]
On Display at Dana QH76.5.I5 P43 2017

Klebsiella pneumoniae activates the innate immune system to reduce tumor burden in models of metastatic lung disease
Costa, Amanda M., author
"There is longstanding appreciation that bacteria-induced immune responses can mediate powerful anti-tumor activity, in both animal models and patients. However, there remains a paucity of safe and effective means to translate these principles into clinical immunotherapy, including the potential risk of administering live organisms, and the limited ability to target tumor-infiltrated organs. We hypothesized that bacteria-induced control of tumors may be achieved and optimized through the repeated stimulation of innate immunity using killed bacteria that are known and common opportunistic pathogens of the cancer-bearing organ. We assessed this possibility using subcutaneous delivery of a product manufactured from inactivated Klebsiella (termed KB), a common lung pathogen, in murine models of metastatic-like lung cancer. KB treatment mediated a significant reduction in lung tumor burden and increased survival that correlated with increased numbers of circulating and lung phagocytic leukocytes, a shift in macrophage polarization, and increased production of cytotoxic effector molecules. KB-mediated anti-tumor efficacy was independent of adaptive immunity, but dependent on the presence of NK cells. Interestingly, we observed an up-regulation of NKG2D ligands, suggesting that KB treatment enhances tumor susceptibility to NK-mediated lysis. Collectively, these data demonstrate preclinical efficacy of an innovative cancer immunotherapy strategy that exploits the potent innate anti-tumor immune mechanisms to improve cancer prognosis."
Rauner D.C. Hist Thesis Masters 2017

This page was dynamically generated on 19-Aug-2017 using data collected at the end of July 2017.